Research study opportunities

The Imaging Dementia — Evidence for Amyloid Scanning (IDEAS) Study is working with researchers to expand the impact of the core study where over 18,000 people with an unclear diagnosis will receive an amyloid PET scan.

Here you will find information about three IDEAS Add-On Studies, approved by the IDEAS Study team, for which you may qualify. You can take part in as many of these studies as you’d like, even if you’re already participating in another clinical trial or research study.

We hope you will consider participating in these important studies to help scientists expand their understanding of the aging brain and provide insight for potential dementia treatments. To date, the three correlative studies below have been approved by the IDEAS Research & Publication Committee.


Three pairs of images from six brain amyloid PET scans. Each pair utilizes a different PET imaging ligand. "Negative" means the person has little or no beta amyloid neuritic plaques in the brain. "Positive" indicates the person has moderate to high levels of beta amyloid neuritic plaques in the brain. These images do not reflect IDEAS-Study participants.

Photo Credit: Alzheimer's Association/IDEAS-Study. The images are used with permission from left to right by Piramal Imaging, Avid Radiopharmaceuticals and GE Healthcare.

ADD-ON STUDIES

The Brain Health Registry (BHR)

The BHR is an online registry and database for recruiting, screening and monitoring progression of brain diseases in participants for clinical neuroscience studies.

BHR collects longitudinal health, lifestyle, medical history and cognitive data from IDEAS participants. Data is collected using self-report online questionnaires and self-administered online neuropsychological tests (NPTs) and will be correlated with the amyloid PET results from the IDEAS Study. This study is funded by the Alzheimer’s Association.

Amyloid Neuroimaging and Genetics Initiative (ANGI)

ANGI focuses on the study of genetic information from IDEAS participants through the collection of saliva for DNA extraction from more than 3,000 subjects.

ANGI will be run by The National Cell Repository for Alzheimer Disease (NCRAD), located at Indiana University and the collection and storage of the samples is funded by the Alzheimer’s Association.

Caregivers' Reactions and Experience: Imaging Dementia - Evidence for Amyloid Scanning (CARE IDEAS) Study

The CARE IDEAS study integrates basic clinical science questions with social and behavioral science data on how patients and caregivers make decisions about and cope with the onset and progression of Alzheimer’s disease.

This project will recruit and survey 2,500 patients and spouses, building upon and complementing the core IDEAS study. This study is funded by the NIH.

How to get involved

If you have immediate questions, please call the IDEAS Add-On Study information line at 888.270.7606.

All participation in ANGI is done by phone and mail, or online. Subjects who express interest in ANGI will be asked to read and sign an informed consent form, share their contact and demographic information and provide a saliva sample. The saliva kit will be mailed to the National Cell Repository for Alzheimer’s Disease at Indiana University, where DNA will be extracted from the saliva sample and stored for future research use.

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