Educational Workshop: The Basics of Fluid Biomarkers in Alzheimer’s Disease

Friday, July 14, 2017
8 a.m. – 5 p.m.
London, England

 

The fluid biomarkers field for Alzheimer’s disease and related disorders is rapidly expanding. The purpose of this workshop is to provide research investigators, clinicians, residents, fellows and graduate and postgraduate students with an in-depth understanding of the fundamental principles, inherent limitations and clinical and research applications of the most common biomarkers used in Alzheimer's disease (AD) and found in cerebrospinal fluid (CSF) and blood. This workshop will include the fundamentals of CSF physiology, basics of neurochemistry, technical issues of sample collection, storage, analysis methods, quality control and regulatory issues. It will also cover the latest in cutting edge biomarker technology including blood-based biomarkers with the current understanding of how biomarkers track the progression in AD and their use in other dementias. Lectures will be followed by interactive sessions to ensure that participants gain in depth understanding of the proper use of fluid biomarkers.

This workshop is organized by leading scientists in the field and by the Alzheimer’s Association Global Biomarkers Standardization Consortia (GBSC) and the ISTAART Biofluid Based Biomarkers PIA.

Organizing Committee

Agenda
  • Time
  • Topics

8 a.m.

Welcome / Introduction


8:15 a.m.

Topic 1: Introduction to CSF Physiology
Markus Otto


8:45 a.m.

Topic 2: Basic Neurochemical Analysis
Kaj Blennow


9:45 a.m.

Topic 3: Analytical Techniques for Biomarker Measurement
Ulf Andreasson


10:30 a.m.

Refreshments


11 a.m.

Topic 4: Operational Issues (Sample Collection, LP’s, Storage)
Charlotte Teunissen


11:45 a.m.

Topic 5: Standardization, Quality Control and Regulatory Issues for Fluid Biomarkers
Piotr Lewczuk and Robert Dean


12:30 p.m.

Lunch


2 p.m.

Topic 6: Current Clinical Use of Fluid Biomarkers for AD & Differential Diagnosis in Dementia (Case-based approach)
Piotr Lewczuk and Jonathan Schott


2:45 p.m.

Topic 7: Emerging Clinical Use of Fluid Biomarkers for AD & Dementia
Henrik Zetterberg


3:30 p.m.

Refreshments


3:45 p.m.

Topic 8: Cutting Edge Techniques Including Blood Based Biomarkers
Sid O’Bryant


4:30 p.m.

Review and quiz


5 p.m.

Closing Remarks


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