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Saturday, June 9, 2007

Preconference

8:30 a.m.–5:30 p.m. Beyond Magic Bullets to Beta-amyloid: Targeting Multiple Neurodegenerative Pathways for Alzheimer Drug Discovery

Chairs
Virginia M.-Y. Lee, University of Pennsylvania, Philadelphia, Pa., United States
John Q. Trojanowski, University of Pennsylvania, Philadelphia, Pa., United States

Course overview

Learning objectives

Target audience

Continuing education

Program Agenda

8:30–8:45 a.m. Introduction to the Program

John Q. Trojanowski,University of Pennsylvania, Philadelphia, Pa., United States

Tau Focused Therapies

8:45–9:15 a.m. Introduction/Overview

Virginia M.-Y. Lee, University of Pennsylvania, Philadelphia, Pa., United States

9:15–9:45 a.m. Do Selective Inhibitors Discern the Relative Roles of Kinases in the Regulation of Tau Phosphorylation?

Joel B. Schachter, CNS Discovery, Global Research and Development, Pfizer, Inc, Groton, Conn., United States

9:45–10:15 a.m. Small-molecule Probes of Tau Fibrillization

Jeff Kuret, Ohio State University, Columbus, Ohio, United States

10:15–10:45 a.m. Break

Cholesterol Modulators

10:45–11:15 a.m. Introduction/Overview

Samuel E. Gandy, Thomas Jefferson Medical School, Philadelphia, Pa., United States

11:15–11:45 a.m. Mechanisms of Statins

Tobias Hartmann, Intitute for Neurobiology, University of Saarland, Hamburg (Saar), Germany

11:45–12:15 p.m. Discussion

Program chairs and participants

12:15–1:45 p.m. Lunch

Anti-inflammation Agents and Antioxidants

1:45–2:15 p.m. Introduction/Overview

Greg Cole, GRECC, University of California, Los Angeles, Calif., United States

2:15–2:45 p.m. Antioxidant Therapies

Domenico Pratico, University of Pennsylvania, Philadelphia, Pa., United States

2:45–3:15 p.m. Caloric Restriction

Mark Mattson, National Institute of Aging, Baltimore, Md., United States

3:15–3:45 p.m. Break

Non-pharmacological Interventions

3:45–4:15 p.m. Introduction/Overview

Colin Masters, University of Melbourne, Melbourne, Australia

4:15–4:45 p.m. Enriched Environments

Orly Lazarov, University of Illinois at Chicago, Chicago, Ill., United States

4:45–5:15 p.m. Natural Products

Hiroyuki Arai, Tohoku University, Sendai, Miyagi, Japan

5:15–5:30 p.m. Closing Comments/Discussion

Program chairs and participants