Grant Portfolio

This one-page overview summarizes portfolio benchmarks, grants by category and major 2004 research themes.
Overview  (1 page)

2004 Grants Organized by Research Themes

This two-column formatted, six-page list groups 2004 grants by general research themes.
2004 Grants (6 pages)

2004 Grants by Country and State

The following research grants — listed by country and state — were awarded by the Alzheimer’s Association during the 2004 grant cycle.

AUSTRALIA

Michael S. Clark, Ph.D.
Flinders University
Adelaide, Australia
Allostatic Load as a Predictor of Poor Health for Dementia Caregivers
Investigator-Initiated Research Grant — $230,716 over three years

CANADA

Ronald M. Baecker, Ph.D.
University of Toronto
Toronto, Ontario, Canada
Internet Multimedia Technology to Support Alzheimer Caregivers and Families
Everyday Technologies for Alzheimer Care Grant — $185,130 over three years

Alex Mihailidis, Ph.D.
University of Toronto
Toronto, Ontario, Canada
An Intelligent Environment to Support Aging-in-Place and Independence
Everyday Technologies for Alzheimer Care Grant — $172,558 over three years

Stephen Pasternak, M.D., C.M., Ph.D.
University of Western Ontario
Toronto, Ontario, Canada
Characterizing the Endosomal / Lysosomal Production of Beta-Amyloid
New Investigator Research Grant — $99,806 over two years

Nicolaas P.L.G. Verhoeff, M.D., Ph.D., F.R.C.P.C., D.A.B.P.N.
Baycrest Centre for Geriatric Care
Toronto, Ontario, Canada
Beta-Amyloid PET Imaging in Alzheimer’s Disease
New Investigator Research Grant — $99,913 over two years
Supported through the generosity of the Blanchette Hooker Rockefeller Fund

CHINA

Huali Wang, M.D., Ph.D.
Peking University Institute of Mental Health
Beijing, China
Dementia Caregiving and Care-Seeking Experiences in Chinese Culture
New Investigator Research Grant — $99,794 over two years

FINLAND

Hilkka S. Soininen, M.D., Ph.D.
University of Kuopio
Kuopio, Finland
Cardiovascular and Lifestyle Risk Factors of Alzheimer’s Disease
Investigator-Initiated Research Grant — $240,000 over three years

FRANCE

Alain Israel, Ph.D.
Institut Pasteur
Paris, France
Genetic Analysis of Gamma-Secretase Activity in Mammalian Cells
Investigator-Initiated Research Grant — $237,600 over three years
Supported through the generosity of the Quest for a Cure Campaign *

ISRAEL

Alon Monsonego, Ph.D.
Ben Gurion University of the Negev
Beersheva, Israel
Investigation of ABeta-Reactive T Cells in a Mouse Model of Alzheimer’s Disease
Investigator-Initiated Research Grant — $240,000 over three years

ITALY

Tommaso Russo, M.D.
CEINGE Biotecnologie Avanzate
Naples, Italy
Regulation of Gene Expression by APP-Fe65 Complex
Investigator-Initiated Research Grant — $239,800 over three years
Supported through the generosity of The Directors' Fund

SPAIN

Douglas V. Laurents, Ph.D.
Instituto de Química-Física
Madrid, Spain
High Resolution Structure of Abeta Peptide Oligomers by NMR
New Investigator Research Grant — $99,897 over two years

UNITED KINGDOM

Alan F. Newell, Ph.D.
University of Dundee
Dundee, Scotland
Digital Television Agents as Prompts for Daily Living
Everyday Technologies for Alzheimer Care Grant — $199,718 over three years

Martin J. Prince, M.D., M.Sc., M.R.C.Psych.
Institute of Psychiatry, King’s College London
London, England
Dementia Care in Mexico, Peru and Argentina
Investigator-Initiated Research Grant — $224,400 over three years

UNITED STATES

Alabama

Gail V. W. Johnson, Ph.D.
University of Alabama at Birmingham
Birmingham, Alabama
Tau Phosphorylation and Caspase Cleavage in Disease Pathogenesis
Investigator-Initiated Research Grant — $119,280 over three years
Supported through the generosity of the Quest for a Cure Campaign *

Arizona

Dr. Donald J. Connor, Ph.D., Ph.D.
Sun Health Research Institute
Sun City, Arizona
Assessment of Cognitive Status in American Indian Populations
New Investigator Research Grant — $100,000 over two years
Supported through the generosity of the Hille Family Foundation

California

John A. Capitman, Ph.D.
California State University
Fresno, California
Racial / Ethnic Minority Senior Housing Residents with Dementia
Investigator-Initiated Research Grant — $239,974 over three years

Dolores E. Gallagher-Thompson, Ph.D.
Stanford University
Stanford, California
Skill-Building to Reduce Distress in Chinese Dementia Family Caregivers
Investigator-Initiated Research Grant — $240,000 over three years

Veronica Galvan, Ph.D.
Buck Institute for Age Research
Novato, California
A Role for the Intracytoplasmic Cleavage of APP in Alzheimer’s Disease
New Investigator Research Grant — $99,140 over two years

Michael D. Greicius, M.D., M.P.H.
Stanford University
Stanford, California
A Novel fMRI Biomarker of Incipient Alzheimer’s Disease
New Investigator Research Grant — $99,532 over two years

Edward H. Koo, M.D.
University of California at San Diego
La Jolla, California
APP Cytoplasmic Domain and Cell Death
Investigator-Initiated Research Grant — $240,000 over three years

Benoit Melchior, Ph.D.
The Scripps Research Institute
La Jolla, California
TREM-2-Mediated Activation of Microglia
New Investigator Research Grant — $99,626 over two years

Christian J. Pike, Ph.D.
University of Southern California
Los Angeles, California
The Role of Age-Related Testosterone Depletion in Alzheimer’s Disease
Investigator-Initiated Research Grant — $240,000 over three years

Sandra F. Simmons, Ph.D.
University of California at Los Angeles
Reseda, California
Prevention of Weight Loss in Nursing Home Residents with Dementia
Investigator-Initiated Research Grant — $240,000 over three years

Zhuohua Zhang, Ph.D.
The Burnham Institute
La Jolla, California
DSCR1 and Neuropathology of Alzheimer’s Disease
Investigator-Initiated Research Grant — $240,000 over three years
Supported through Pine Family Foundation *

District of Columbia

Mark P. Burns, Ph.D.
Georgetown University
Washington, D.C.
Cholesterol, Statins and Secretase Activity
Investigator-Initiated Research Grant — $239,952 over three years
Supported through the generosity of the Hille Family Foundation

Florida

Ruth M. Tappen, Ed.D., R.N., F.A.A.N.
Florida Atlantic University
Boca Raton, Florida
Cognitive Retraining for Individuals with Early-Stage Alzheimer’s Disease
Investigator-Initiated Research Grant — $240,000 over three years

Illinois

Zoe Arvanitakis, M.D.
Rush-Presbyterian-.St. Luke’s Medical Center
Chicago, Illinois
Markers of Oxidative Stress and Mild Cognitive Impairment
New Investigator Research Grant — $99,956 over two years
Supported through the generosity of the Nartel Family Foundation

John M. Lee, M.D., Ph.D.
Loyola University Medical Center
Maywood, Illinois
Effects of Glycosaminoglycans on Alzheimer Pathology and Behavior
Investigator-Initiated Research Grant — $239,959 over three years

Gopal Thinakaran, Ph.D.
University of Chicago
Chicago, Illinois
Mechanisms of Raft Association and Abeta Production by PS1 / Gamma-Secretase
Investigator-Initiated Research Grant — $240,000 over three years

Barbara L. Trommer, M.D.
Evanston Northwestern Healthcare Research Institute
Evanston, Illinois
ApoE Isoform Dependent Susceptibility of LTP to Amyloid Beta
Investigator-Initiated Research Grant — $239,834 over three years

Kentucky

Michal Hetman, M.D., Ph.D.
University of Louisville Research Foundation, Inc.
Louisville, Kentucky
Analysis of NMDAR-GSK3-Alzheimer Disease Connections in Cultured Neurons
Investigator-Initiated Research Grant — $240,000 over three years

Michael P. Murphy, M.A., Ph.D.
University of Kentucky
Lexington, Kentucky
Using Cloning Technology to Create an APP Transgenic Rat
New Investigator Research Grant — $100,000 over two years
Supported through the generosity of the National Association of Retired Federal Employees

Maryland

Changhai Cui, Ph.D.
West Virginia University Research Corporation
Rockville, Maryland
Modulation of GluRs by Soluble Oligomers of Amyloid Beta Peptides
New Investigator Research Grant — $99,998 over two years
Supported through the generosity of the Conrad N. Hilton Foundation in memory of President Ronald Reagan

Philip C. Wong, Ph.D.
Johns Hopkins University
Baltimore, Maryland
Reduction of Gamma-Secretase Activity by RNAi in Brains of Mutant APP / PS1 Mice
Zenith Fellows Award — $250,000 over two years
Supported through the generosity of the Zenith Fellows

Massachusetts

Ashley I. Bush, M.D., Ph.D.
Massachusetts General Hospital
Charlestown, Massachusetts
Novel Imaging Agents for Alzheimer’s Disease
Zenith Fellows Award — $250,000 over two years
Supported through the generosity of the Zenith Fellows

Lee E. Goldstein, M.D., Ph.D.
Brigham and Women’s Hospital
Boston, Massachusetts
Development of a Novel, Noninvasive Alzheimer’s Disease Diagnostic and Monitoring Instrument
Investigator-Initiated Research Grant — $240,000 over three years
Supported through the generosity of Rally for Research

Vernon M. Ingram, Ph.D., D.Sc.
Massachusetts Institute of Technology
Cambridge, Massachusetts
Developing Decoy Peptides and Active Small Molecules for Alzheimer Therapy
Investigator-Initiated Research Grant — $200,000 over two years

Diane F. Mahoney, Ph.D.
Hebrew Rehabilitation Center for Aged
Boston, Massachusetts
Sensors for Seniors with Alzheimer’s Disease: Tailoring Technologies
Everyday Technologies for Alzheimer Care Grant — $199,999 over three years

Timothy J. Seabrook, B.M.L.Sc., Ph.D.
Brigham and Women’s Hospital
Boston, Massachusetts
Modulation of Microglia Activation: A Potential Therapeutic for Alzheimer’s Disease
New Investigator Research Grant — $99,994 over two years
Supported through the generosity of the Hille Family Foundation

Jie Shen, Ph.D.
Brigham and Women’s Hospital
Boston, Massachusetts
Role of Presenilin-1 Mutation in Synaptic Dysfunction and Alzheimer’s Disease Pathogenesis
Investigator-Initiated Research Grant — $240,000 over three years

Michigan

Daniel L. Murman, M.D., M.S.
Michigan State University
East Lansing, Michigan
Quality Indicators in Ambulatory Dementia Care
Senator Mark Hatfield Award for Clinical Research in Alzheimer’s Disease — $239,953 over three years

Missouri

Guojun Bu, Ph.D.
Washington University
St. Louis, Missouri
Role of LRP1B in APP Trafficking and Alzheimer’s Disease
Investigator-Initiated Research Grant — $239,993 over three years
Supported through the generosity of Charles and Joanne Knight and the Emerson Electric Company in care of the Alzheimer's Association - St. Louis Chapter

New York

Apostolia Baki, Ph.D.
Mount Sinai School of Medicine
New York, New York
PS1 Prevents Development of Alzheimer’s Disease Pathological Hallmarks via PI3K Signaling
New Investigator Research Grant — $100,000 over two years
Supported through the generosity of the Pine Family Foundation *

Karen Duff, Ph.D.
The Nathan Kline Institute
Orangeburg, New York
Kinase Inhibitors for the Treatment of Tangles
Investigator-Initiated Research Grant — $249,860 over two years
Supported through the generosity of Margaret Cahn

Voyko Kavcic, Ph.D.
University of Rochester
Rochester, New York
Early Detection of Alzheimer’s Disease with Diffusion Tensor Imaging and Behavioral Testing
New Investigator Research Grant — $98,531 over two years
Supported through the generosity of the Ambrose Monell Foundation *

Adrian Leibovici, M.D.
University of Rochester
Rochester, New York
Assessment and Monitoring of Non-Cognitive Symptoms of Dementia
Everyday Technologies for Alzheimer Care Grant — $199,626 over three years

Yueming Li, Ph.D.
Sloan-Kettering Institute for Cancer Research
New York, New York
Defining the Catalytic Machinery of Secretasome for Alzheimer’s Disease Therapy
Zenith Fellows Award — $250,000 over two years
Supported through the generosity of the Zenith Fellows

Mary S. Mittelman, M.S., Dr.P.H.
New York University
New York, New York
Couples Counseling for People with Alzheimer’s Disease and their Spouses: A Randomized Trial
Zenith Fellows Award — $249,985 over two years
Supported through the generosity of the Zenith Fellows

Jay Nierenberg, M.D., Ph.D.
The Nathan Klein Institute
Orangeburg, New York
MRI and MRSI of Subjects with ApoE Genotype
New Investigator Research Grant — $100,000 over two years

Anita Ramani, M.Sc., Ph.D.
New York University
New York, New York
Quantitative Magnetization Transfer Measurements in Alzheimer’s Disease
New Investigator Research Grant — $100,000 over two years

Agueda Rostagno, Ph.D.
New York University
New York, New York
Amyloidogenic Peptides: Conformational Modifiers, Inflammation and Toxicity
Investigator-Initiated Research Grant — $240,000 over three years

Einar M. Sigurdsson, Ph.D.
New York University
New York, New York
Abeta Derivatives as Safer Vaccines for Alzheimer’s Disease
Investigator-Initiated Research Grant — $240,000 over three years
Supported through the generosity of the National Association of Retired Federal Employees

Jeremy M. Silverman, Ph.D.
Mount Sinai School of Medicine
New York, New York
Successful Cognitive Aging Phenotypes in a Genetically Isolated Population
Investigator-Initiated Research Grant — $240,000 over three years
Supported through the generosity of the Quest for a Cure Campaign *

Nikalaos Scarmeas, Ph.D.
Columbia University
New York, New York
Early Alzheimer’s Disease Detection via Arterial Spin Labeling MRI and Covariance Analyses
Investigator-Initiated Research Grant — $239,475 over three years

Daryl Spinner, Ph.D.
Research Foundation for Mental Hygiene at the New York State Institute for Basic Research
Staten Island, New York
Effect of TLR Signaling on Microglia and Alzheimer's Disease Progression
New Investigator Research Grant — $100,000 over two years
Supported through the generosity of The Stranahan Foundation

Sidney Strickland, Ph.D.
Rockefeller University
New York, New York
Modulating the tPA / Plasmin System to Facilitate Beta-Amyloid Clearance
Investigator-Initiated Research Grant — $239,998 over three years
Supported through the generosity of the Hille Family Foundation

Daniel H. Turnbull, Ph.D.
New York University
New York, New York
MRI Detection of Alzheimer’s Amyloid
Investigator-Initiated Research Grant — $240,000 over three years
Supported through the generosity of Margaret Cahn

North Carolina

Kevin S. LaBar, Ph.D.
Duke University
Durham, North Carolina
Early Detection of Amygdala Dysfunction in Alzheimer’s Disease
New Investigator Research Grant — $99,000 over two years

Frank M. Longo, M.D., Ph.D.
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina
Prevention of Abeta-Induced Degeneration with Neurotrophin Domain Mimetics
Investigator-Initiated Research Grant — $240,000 over three years
Supported through the generosity of the Scholtz Family Foundation and the Hille Family Foundation

Philip D. Sloane, M.D., M.P.H.
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina
Improving Medical Care of Assisted Living Residents with Dementia
Pioneer Award for Alzheimer’s Disease Research — $1,000,000 over five years
Supported through the generosity of the Judy Fund

Patrick M. Sullivan, Ph.D.
Duke University
Durham, North Carolina
Effect of Diet and APOE Genotype on Susceptibility to Alzheimer’s Disease
Investigator-Initiated Research Grant — $240,000 over three years
Supported through the generosity of the Quest for a Cure Campaign *

Ohio

Karl Herrup, Ph.D.
Case Western Reserve University
Cleveland, Ohio
Cell Cycle Events as Outcome Measures in Alzheimer’s Preclinical Studies
Investigator-Initiated Research Grant — $237,600 over three years

George Perry, Ph.D.
Case Western Reserve University
Cleveland, Ohio
Phosphorylation Dependency of Protein Oxidation
Investigator-Initiated Research Grant — $240,000 over three years

Pennsylvania

Brian J. Balin, Ph.D.
Philadelphia College of Osteopathic Medicine
Philadelphia, Pennsylvania
Chlamydia Pneumoniae Infection of Mice Triggers Alzheimer-Like Pathology
Investigator-Initiated Research Grant — $240,000 over three years

Tania Giovannetti, Ph.D.
Temple University
Philadelphia, Pennsylvania
Improving Everyday Action Through Strategic Object Placement
New Investigator Research Grant — $99,738 over two years

Randy S. Hebert, M.D., M.P.H.
University of Pittsburgh
Pittsburgh, Pennsylvania
Spirituality, Health and Health Service Use Among Dementia Caregivers
New Investigator Research Grant — $63,241 over two years

Tennessee

Randy D. Blakely, Ph.D.
Vanderbilt University
Nashville, Tennessee
A Chemical Genetic Screen for Modifiers of Presynaptic Choline Transport
Zenith Fellows Award — $250,000 over two years
Supported through the generosity of the Zenith Fellows

Texas

Jochen Klein, Ph.D., D.Sc.
Texas Tech University Health Sciences Center
Amarillo, Texas
Amyloid Deposition and Central Cholinergic Activity
Investigator-Initiated Research Grant — $146,424 over two years

Myron F. Weiner, M.D.
University of Texas Southwestern Medical School
Dallas, Texas
Cardiovascular Risk Factors and Alzheimer Disease in Native Americans
Investigator-Initiated Research Grant — $239,676 over three years

Washington

Laura D. Baker, M.A., Ph.D.
University of Washington
Tacoma, Washington
Cognitive Effects of Aerobic Exercise for Prodromal Alzheimer’s Disease: A Controlled Trial
New Investigator Research Grant — $100,000 over two years

Paul K. Crane, M.D., M.P.H.
University of Washington
Seattle, Washington
Acculturation and Alzheimer’s Disease Risk Among Japanese and Japanese-American Elderly
Investigator-Initiated Research Grant — $239,953 over three years

Pamela J. McMillan, Ph.D.
Seattle Institute for Biomedical and Clinical Research
Seattle, Washington
Effect of APOE on IDE and Insulin Signaling in Alzheimer’s Disease
New Investigator Research Grant — $100,000 over two years
Supported through the generosity of the Clients of Mary Keane and the Alzheimer's Association - Western and Central Washington State Chapter