Scientific Sessions





Scientific Sessions

The schedule below reflects the invited program only. The complete schedule, including the submitted program, will be available closer to the conference.

Plenary Sessions

10:30 - 11:15 a.m.

Association Welcome

Session: PL-01-01

11:15 - 11:45 a.m.

Aberrant Network Activity in Alzheimer’s Disease – Preclinical Investigation to Clinical Trials

Lennart Mucke, M.D.
Gladstone Institute of Neurological Disease, United States
Theme: Therapeutics
Session: PL-01-02

10:30 – 11 a.m.

Multimodal Lifestyle Interventions

Miia Kivipelto, Ph.D.
Karolinska Institutet; Karolinska University Hospital, Sweden
Theme: Therapeutics
Session: PL-02-01

11 - 11:30 a.m.

The Aging Brain and the Risk for Alzheimer’s Disease

Denise Park, Ph.D.
The University of Texas, Dallas, United States
Theme: Diagnosis and Prognosis
Session: PL-02-02

10:30 - 11 a.m.

Inge Grundke-Iqbal Award for Alzheimer’s Research

To be announced.

Session: PL-03-01

11 - 11:30 a.m.

Psychosocial Research in Dementia: Past, Present and Future

Henry Brodaty, M.D.
UNSW Sydney, Australia
Theme: Public Health and Psychosocial
Session: PL-03-02

10:30 - 11 a.m.

Pathobiology of ApoE in Alzheimer’s Disease

Guojun Bu, Ph.D.
Mayo Clinic, United States
Theme: Diagnosis and Prognosis
Session: PL-04-01

11 - 11:30 a.m.

Communication Between the Immune System and the Brain

Michal Schwartz, Ph.D.
Weizmann Institute of Science, Israel
Theme: Basic and Translational Science
Session: PL-04-02

10:30 - 11:00 a.m.

Pathogenesis of Alzheimer's Disease: What Have We Learned From Neuroimaging?

Gil Rabinovici, M.D.
Memory and Aging Center, University of California, San Francisco, United States
Theme: Diagnosis and Prognosis
Session: PL-05-01

11:00 - 11:30 a.m.

AD Biomarker Epidemiology in the Aging Population: Prevalence, Risk Factors and Outcomes

Prashanthi Vemuri, Ph.D.
Mayo Clinic, United States
Theme: Public Health & Psychosocial
Session: PL-05-02

Symposium Sessions

Sunday, July 22
  • 8 - 9:30 a.m.
    Innovative Approaches In Epidemiology
    Theme: Public Health and Psychosocial Factors / Epidemiology
    Session S1-01



Approaches to Harmonize Neuropsychological Data Across Studies

Nicole Kochan
Centre for Healthy Brain Ageing, UNSW;
Neuropsychiatric Institute, Prince of Wales Hospital, Australia

Alternatives to Randomized Trials Using Simulations and Observational Data

Chung-Chou Chang
University of Pittsburgh
Graduate School of Public Health, United States

Analysis of Data from Wearable Devices

Aron Buchman
Rush Alzheimer's Disease Center;
Rush University Medical Center, United States

Epidemiology in the Era of Big Data

Robert Stewart
King’s College
London, United Kingdom

Sunday, July 22
  • 8 - 9:30 a.m.
    Genetic and Biological Validation of Alzheimer GWAS Genes and Their Contribution to Disease
    Theme: Basic and Translational Science / Genetics
    Session: S1-02



Review of GWAS Genes and Polygenic Risk Scores

Carlos Cruchaga
Washington University
School of Medicine, United States

Approaches Towards Understanding the Pathomechanism Underlying GWAS Gene Associations

Steven Estus
Center on Aging, United States

Genetics of SORL1 and Its Role As APP Neuronal Sorting Receptor

Ekaterina Rogaeva
University of Toronto, Canada

Complex Mutations in ABCA7 Modify Disease Penetrance By Dosage Reduction

Kristel Sleegers
Institute Born-Bunge,
University of Antwerp;
Neurodegenerative Brain Diseases Group,
Center for Molecular Neurology, VIB, Belgium

Monday, July 23
  • 8 - 9:30 a.m.
    Linking Neuroimaging To Neuropathology Of Tau
    Theme: Diagnosis and Prognosis / Neuroimaging
    Session: S2-01



Tau Pathology of Alzheimer's Disease

Charles Duyckaerts
Laboratoire de neuropathologie
Raymond Escourolle, France

Origins of Tau Accumulation

Lea Grinberg
University of California,
San Francisco, United States;
University of São Paulo Medical School, Brazil

Linking Post-Mortem MRI and Dense Histology

Paul Yushkevich
Penn Image Computing and Science Laboratory (PICSL),
University of Pennsylvania, United States

Tau Dissemination Patterns in the Brain Before and After Dementia

Val Lowe
Mayo Clinic, United States

Monday, July 23
  • 8 - 9:30 a.m.
    Translational Research In Reality—What Are The Criteria From Concept To Clinic?
    Theme/Topic: Therapeutics / Clinical
    Session: S2-02



New In Vivo Models for Alzheimer’s Disease – MODEL-AD

Bruce Lamb
Indiana University,
Stark Neurosciences Research Institute, United States

Translational Research – The View from Pharma

Samantha Budd Haeberlein
Biogen, United States

Progression of Synaptoprotective Sigma-2 Antagonists into the Clinic

Susan Catalano
Cognition Therapeutics Inc., United States

Targeting the p75 Neurotrophin Receptor – A New Approach for Alzheimer’s Disease

Frank Longo
Stanford University, United States

Tuesday, July 24
  • 8 - 9:30 a.m.
    Apolipoprotein E & Dementia: Mechanisms, Risk And Therapy
    Theme/Topic: Diagnosis and Prognosis / Neuropathology
    Session: S3-01



Effects of ApoE on Tau Mediated Neurodegeneration

David Holtzman
Washington University, United States

Apoe and Alzheimer’s Disease Imaging Biomarkers

Beth Mormino
Massachusetts General Hospital, United States

Apoe and Sex Differences on Alzheimer’s Disease Risk

Arthur Toga
University of Southern California, United States

Therapeutic Strategies: Apoe in Traumatic Brain Injury

Cheryl Wellington
University of British Columbia, Canada

Tuesday, July 24
  • 8 - 9:30 a.m.
    Mechanisms Of Neuronal Death
    Theme/Topic: Therapeutics / Preclinical (nonhuman)
    Session: S3-02



Necroptosis Activation in Alzheimer’s Disease

Antonella Caccamo
Arizona State University, United States

Stress Granule Formation and Neuronal Death

Benjamin Wolozin
Boston University School of Medicine, United States

Neuroinflammatory Processes and Neurodegeneration

Roisin McManus
German Center for Neurodegenerative Diseases (DZNE), Germany

Microglial Activation in Neurodegenerative Diseases: Opportunities for Therapeutic Intervention

Diego Gomez-Nicola
University of Southampton, United Kingdom

Wednesday, July 25
  • 8 - 9:30 a.m.
    Environmental Risk Factors For Alzheimer’s Disease
    Theme/Topic: Public Health and Psychosocial Factors / Psychosocial Factors and Environmental Design
    Session: S4-01



The Relation Between Air Pollution Exposure and Dementia

Jennifer Weuve
Boston University School of Public Health, United States

Interaction between Pollutant Exposures and Genetics in Aging Populations at Risk for Cognitive Decline

Kelly Bakulski
University of Michigan, United States

Traffic Noise Exposure and Mild Cognitive Impairment

Lilian Tzivian
University of Lativia, Lativia

Thursday, July 26
  • 8:30 – 10 a.m.
    Role of Glial Cells in Neurodegeneration
    Theme/Topic: Basic and Translational Science / Molecular and Cell Biology
    Session: S5-01



Ageing and Neuroimmunology: The White Matter Pathology

Julie Simpson
University of Sheffield, United Kingdom

Astrocytes in Alzheimer’s Disease - Molecular Changes and Functional Consequences

Elly Hol
Brain Center Rudolf Magnus,
UMC Utrecht, Netherlands

Oligodendrocytes in Dementia

Ragnhildur Thora Karadottir
University of Cambridge,
United Kingdom

Join the Conversation #AAIC18






> 1200px
> 992px
> 768px
< 767px