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Research Grants 2009

To view an abstract, select an author from the vertical list on the left.

2009 Grants - Buettner

Mentally Stimulating Activities (MSAs) to Treat Apathy in Early Stage Alzheimer's Disease

Linda L. Buettner, Ph.D.
The University of North Carolina at Greensboro
Greensboro, North Carolina

2009 Investigator-Initiated Research Grant

Apathy (the loss of motivation) is the most common neuropsychiatric symptom in mild to moderate stages of Alzheimer's, and it increases in severity as the dementia progresses. Apathy is complex to treat since it is often mixed with other behaviors, and evidence shows pharmacological therapies are not particularly effective in managing symptoms.

People with Alzheimer's disease who have apathy require more management and support due to their reliance on others to schedule their activities and initiate tasks even when they are still physically capable of performing them. Studies have shown that apathy was consistently associated with more severe functional impairments, more severe cognitive deficits and higher levels of burden and distress in caregivers.

Based on preliminary work, Linda L. Buettner and colleagues believe that they can reduce symptoms of apathy and improve functional outcomes for individuals with early stage Alzheimer's by using a mentally stimulating activity (MSA) intervention program. The researchers hypothesize that finding interventions to address apathy symptoms during the early stages of Alzheimer's could help maintain function, improve outcomes during treatment, reduce related behavioral symptoms and improve quality of life for families.

Alzheimer's Association International Conference | July 16-20, 2017, London, England

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