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2015 Grants - Bhattacharjee
Comparative Effectiveness of Medications to Treat Alzheimer’s Disease
Sandipan Bhattacharjee, Ph.D.
University of Arizona
2015 New Investigator Research Grant
Which approved medications to treat Alzheimer’s symptoms are the most effective?
A limited number of medications have been FDA-approved to treat the symptoms of Alzheimer’s disease, and the available medications only reduce symptoms for a limited time in about half of people who use them. Furthermore, there are limited studies available that directly compare these medications to guide health care providers in determining which are most effective for people with specific characteristics or stages of disease.
Sandipan Bhattacharjee, Ph.D., and colleagues have proposed a study to compare the effectiveness of available Alzheimer’s medications. They will use existing data from the Medicare system that contains records of people diagnosed with Alzheimer’s. This system also records what treatments they have been prescribed and valuable information that could indicate poor symptom control, such as disability, hospitalization, falls and fractures. Dr. Bhattacharjee and colleagues will use Medicare data to study how well the prescribed medications were associated with reduced rates of these indications in people with Alzheimer’s disease.
These studies could help physicians and other health care providers determine which Alzheimer’s medications are most effective for people with certain characteristics or who are in different stages of the disease. Better informed treatment decisions could lead to improved health outcomes and quality of life for people with Alzheimer’s disease.